Renin in critically ill patients

Abstract The renin-angiotensin system (RAS) constitutes one of the principal mechanisms to maintain hemodynamic and fluid Supports homeostasis.However, most research until now on RAS primarily focuses on its relationship with hypertension and its role in critically ill hypotensive populations is not well understood.With the approval of angiotensin

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Reduction in number to treat versus number needed to treat

Abstract Background We propose a new measure of treatment effect based on the expected reduction in the number of patients to treat (RNT) which is defined as the difference of the reciprocals of clinical measures of interest between two arms.Compared with the conventional number needed to treat (NNT), RNT shows superiority with both binary and time

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